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Man recounts pushing fiancee away from car during protest

CHARLOTTESVILLE, Va. (AP) — With tires screeching and bodies flying, Marcus Martin shoved his fiancee out of the way of a car charging through a crowd of peaceful protesters in Charlottesville, Virginia. Marcus Martin was promptly hit and upended by the car as it plowed through the crowd. Flat on his back with a broken leg, he says he experienced several minutes of terror. “The only thing running through my mind was: please don’t let her be dead,” Martin, 26, told The Associated Press in … Read the referenced story here:…

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Business 

Doctor Saves Woman Who Reportedly Overdosed During Spirit Airlines Flight

A local doctor was credited with saving a life this week after he helped a woman who is believed to have overdosed Friday on a Minneapolis-bound Spirit Airlines flight from Boston. Dr. Anil Punjabi, a Boston cardiologist, and a number of other crew and passengers worked to keep the woman alive for 25 minutes as the plane made an emergency landing. The woman, who was not identified, visited the plane’s lavatory for a lengthy period of time before other passengers alerted crew aboard the flight, Fox-affiliate WFXT reported Monday. When…

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[Report] Layer-specific modulation of neocortical dendritic inhibition during active wakefulness

γ-Aminobutyric acid (GABA)ergic inputs are strategically positioned to gate synaptic integration along the dendritic arbor of pyramidal cells. However, their spatiotemporal dynamics during behavior are poorly understood. Using an optical-tagging electrophysiological approach to record and label somatostatin-expressing (Sst) interneurons (GABAergic neurons specialized for dendritic inhibition), we discovered a layer-specific modulation of their activity in behaving mice. Sst interneuron subtypes, residing in different cortical layers and innervating complementary laminar domains, exhibited opposite activity changes during transitions to active wakefulness. The relative weight of vasoactive intestinal peptide–expressing (Vip) interneuron–mediated inhibition of distinct…

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